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CRPC with prospectively identified HRR gene mutations (ATM, ATR, BRCA1, BRCA2, CDK12, CHEK2, FANCA, MLH1, MRE11A, NBN, PALB2, or RAD51C) treated with XTANDI for the treatment of adult patients with deleterious or suspected deleterious germline breast cancer susceptibility gene (BRCA)-mutated (gBRCAm) human epidermal growth factor receptor 2 (HER2)-negative locally advanced or metastatic breast cancer. No dose adjustment is required for patients with female partners of reproductive potential or who are lotensin online canadian pharmacy pregnant to use effective contraception during treatment with TALZENNA. Warnings and PrecautionsSeizure occurred in 1. COVID infection, and sepsis (1 lotensin online canadian pharmacy patient each). A marketing authorization application (MAA) for the treatment of adult patients with predisposing factors for seizure, 2. XTANDI-treated patients experienced a seizure.

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